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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
HMGBiotech/BoxA 2D (negative control of BoxA wt), LPS-free (25 µg) [HM-193]/negative control of BoxA wt), LPS-free (25 µg/HM-193
产品编号:HM-193
市  场 价:¥2100.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$105.00
品      牌: HMGBiotech
公      司:HMGBiotech
公司分类:
HMGBiotech/BoxA 2D (negative control of BoxA wt), LPS-free (25 µg) [HM-193]/negative control of BoxA wt), LPS-free (25 µg/HM-193
商品介绍

Description

BoxA 2D (negative control of BoxA wt), LPS-free (25 µg) [HM-193]

BoxA 2D is the mutant form of BoxA (DNA binding domains of HMGB1 protein) in which the two cysteines are replaced with aspartic acid.It consists of 89 amino acids and has a calculated molecular mass of approximately 10.4 kDa.BoxA 2D in migration assay cannot block the HMGB1 induced migration of fibroblasts.It contains only trace amounts of LPS (<0.4 ng/mg protein).BoxA 2D variant can be used as negative control of BoxA wt.

It has the sequence:

MGKGDPKKPR GKMSSYAFFV QTDREEHKKK HPDASVNFSE FSKKDSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKF

Molecular Mass: BoxA 2D from HMGB1 consists of 89 amino acid and has a calculated molecular mass of approximately 10.4 kDa.Purity: The purified protein is >98% homogeneous (electrophoresis and mass spectrometry).Endotoxin Level: The purified protein is free from LPS (Cambrex Limulus Amoebocyte Assay QCL-1000, <0.4 ng LPS per mg protein).Buffer: 50 mM HEPES-Na pH 7.9, 500 mM NaCl, 0.5 mM DTT.Storage: the protein is shipped lyophilized. Once resuspended can be stored frozen at -20°C.

This product is intended for research only, and cannot be used on humans.

    Download BoxA 2D Datasheet

Complete Name: BoxA 2D from High Mobility Group 1Other Names: A-Box HMGB1 mutant, Box-A from HMGB1 mutant, BoxA from High Mobility Group 1 mutant, HMGB1 aspartic acid mutant, 2D mutant

品牌介绍

HMGBiotech是一家生物技术公司,由HMGB领域的领先科学家Marco E.Bianchi创建字段.HMGB1是细胞核的组成部分,在基因组的组织和表达中具有多种功能。当一个细胞因损伤(病毒、机械或化学损伤、中毒)而死亡时,HMGB1就会释放出来,并被附近细胞中的受体接收。此外,严重应激下的细胞甚至在死亡前就分泌HMGB1。存活的细胞会产生一种第一线的反应——炎症反应——并试图替换死细胞,重建受损组织。HMGB1促进心脏的恢复和再生,例如梗死后的心脏。然而,过多的HMGB1与脓毒症(过度炎症导致急性疼痛最终死亡)、关节炎、动脉粥样硬化和癌症有关转移srl为活跃在这一领域的其他研究人员和公司提供试剂、服务和想法。它也有助于Bianchi实验室开发分析和试剂.HMGBiotech在意大利米兰莫雷托-达-布雷西亚25号(邮编:20133)设有办事处,在意大利米兰奥盖蒂纳58号皇家空军科技园内设有研发和生产部门。

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